{"id":4445,"date":"2025-10-20T21:31:10","date_gmt":"2025-10-20T13:31:10","guid":{"rendered":"https:\/\/ieohs.nycu.edu.tw\/?p=4445"},"modified":"2025-10-20T21:38:41","modified_gmt":"2025-10-20T13:38:41","slug":"4445","status":"publish","type":"post","link":"https:\/\/ieohs.nycu.edu.tw\/?p=4445","title":{"rendered":""},"content":{"rendered":"\n<h2><strong>\u674e\u5ba5\u8431 \u526f\u6559\u6388<\/strong><\/h2>\n\n\n\n<div class=\"is-content-justification-space-between is-nowrap is-layout-flex wp-container-7 wp-block-group alignwide\">\n<div class=\"is-layout-flex wp-container-3 wp-block-columns are-vertically-aligned-center has-small-font-size\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">\n<div class=\"is-layout-flow wp-block-column is-vertically-aligned-center\">\n<figure class=\"wp-block-image size-full is-resized has-custom-border\"><img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167.jpg\" alt=\"\" class=\"wp-image-4446\" style=\"border-style:none;border-width:0px\" width=\"336\" height=\"448\" srcset=\"https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167.jpg 1630w, https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167-225x300.jpg 225w, https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167-773x1030.jpg 773w, https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167-768x1024.jpg 768w, https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167-1152x1536.jpg 1152w, https:\/\/ieohs.nycu.edu.tw\/wp-content\/uploads\/2025\/10\/\u674e\u5ba5\u8431\u7db2\u9801\u500b\u4eba\u7167-1536x2048.jpg 1536w\" sizes=\"(max-width: 336px) 100vw, 336px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"is-layout-flow wp-block-column is-vertically-aligned-center\" style=\"padding-top:var(--wp--preset--spacing--50);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50);padding-left:var(--wp--preset--spacing--50)\">\n<p><\/p>\n\n\n\n<p class=\"has-large-font-size\"><strong>\u5b78\u6b77<\/strong><\/p>\n\n\n\n<p>\u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u535a\u58eb<\/p>\n\n\n\n<p>\u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u78a9\u58eb<\/p>\n\n\n\n<p>\u4e2d\u5c71\u91ab\u5b78\u5927\u5b78\/\u8077\u696d\u5b89\u5168\u8207\u885b\u751f\u5b78\u7cfb\/\u5b78\u58eb<\/p>\n\n\n\n<p class=\"has-large-font-size\"><strong>\u6280\u8853\u5c08\u9577<\/strong><\/p>\n\n\n\n<ol>\n<li>\u74b0\u5883\u6bd2\u7406\u5b78<\/li>\n\n\n\n<li>\u76ae\u819a\u75be\u75c5\/\u514d\u75ab\u5b78<\/li>\n\n\n\n<li>\u5948\u7c73\u6750\u6599\u61c9\u7528\u8207\u5b89\u5168\u6027\u8a55\u4f30<\/li>\n\n\n\n<li>\u7d30\u80de\u751f\u7269\u5b78<\/li>\n<\/ol>\n\n\n\n<p>email: Yhlee25@nycu.edu.tw<\/p>\n\n\n\n<p>phone: +886-2-2826-7000 #67323<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"is-layout-flex wp-container-6 wp-block-columns\">\n<div class=\"is-layout-flow wp-block-column\">\n<p class=\"has-large-font-size\"><strong>\u7d93\u6b77<\/strong><\/p>\n\n\n\n<div class=\"is-layout-constrained wp-block-group\"><div class=\"wp-block-group__inner-container\">\n<figure class=\"wp-block-table alignright is-style-stripes\"><table><tbody><tr><td class=\"has-text-align-left\" data-align=\"left\">\u670d\u52d9\u6a5f\u95dc<\/td><td>\u670d\u52d9\u90e8\u9580\uff0f\u7cfb\u6240<\/td><td>\u8077\u7a31<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u73fe\u8077\uff1a\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/td><td>\u74b0\u5883\u8207\u8077\u696d\u885b\u751f\u7814\u7a76\u6240<\/td><td>\u526f\u6559\u6388<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u73fe\u8077\uff1a\u53f0\u7063\u6bd2\u7269\u5b78\u5b78\u6703<\/td><td>\u5b78\u8853\u79d1\u6280\u59d4\u54e1\u6703<\/td><td>\u526f\u53ec\u96c6\u4eba<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u4e2d\u570b\u91ab\u85e5\u5927\u5b78<\/td><td>\u85e5\u7528\u5316\u599d\u54c1\u5b78\u7cfb<\/td><td>\u526f\u6559\u6388<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u4e2d\u570b\u91ab\u85e5\u5927\u5b78<\/td><td>\u85e5\u7528\u5316\u599d\u54c1\u5b78\u7cfb<\/td><td>\u52a9\u7406\u6559\u6388<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u570b\u7acb\u6210\u529f\u5927\u5b78<\/td><td>\u98df\u54c1\u5b89\u5168\u885b\u751f\u66a8\u98a8\u96aa\u7ba1\u7406\u7814\u7a76\u6240<\/td><td>\u5c08\u6848\u52a9\u7406\u6559\u6388<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u570b\u7acb\u6210\u529f\u5927\u5b78<\/td><td>\u91ab\u5b78\u9662\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240<\/td><td>\u535a\u58eb\u5f8c\u7814\u7a76\u54e1<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">\u570b\u7acb\u6210\u529f\u5927\u5b78<\/td><td>\u91ab\u5b78\u9662\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240<\/td><td>\u7814\u7a76\u52a9\u7406<\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p><strong>\u7814\u7a76\u65b9\u5411:<\/strong> \u8fd1\u5e74\u4f86\u7684\u7814\u7a76\u91cd\u9ede\u5728\u65bc\u767c\u708e\u53cd\u61c9\u53ca\u75be\u75c5\u7684\u9810\u9632\u6cbb\u7642\uff0c\u5167\u5bb9\u5305\u62ec\u7a7a\u6c23\u4e2d\u7684\u61f8\u6d6e\u5fae\u7c92\u3001\u5851\u81a0\u5fae\u7c92\u3001\u516d\u50f9\u927b\u53ca\u5948\u7c73\u7c92\u5b50\u7b49\u3002\u7814\u7a76\u65b9\u5411\u8457\u91cd\u5728\u767c\u708e\u53cd\u61c9\u7684\u8abf\u63a7\u8207\u76ae\u819a\u3001\u809d\u81df\u3001\u814e\u81df\u6bd2\u6027\u7684\u76f8\u95dc\u6027\u3001\u8abf\u7bc0\u7d30\u80de\u589e\u751f\u53ca\u6b7b\u4ea1\u65b9\u5f0f\uff0c\u4e26\u63a2\u8a0e\u6c27\u5316\u58d3\u529b\u53ca\u91cd\u8981\u8a0a\u606f\u50b3\u905e\u8def\u5f91\u6539\u8b8a\u7b49\u5728\u74b0\u5883\u6bd2\u7269\u6bd2\u6027\u53ca\u75be\u75c5\u7522\u751f\u904e\u7a0b\u7684\u89d2\u8272\u3002<\/p>\n\n\n\n<p class=\"has-large-font-size\">\u7372\u734e\u7d00\u9304<\/p>\n\n\n\n<p class=\"has-large-font-size\"><strong>\u7372\u734e\u7d00\u9304<\/strong><\/p>\n\n\n\n<p>1.&nbsp; 2014\u5e74\u570b\u7acb\u6210\u529f\u5927\u5b78\u512a\u79c0\u8ad6\u6587\u7af6\u8cfd \u512a\u52dd<\/p>\n\n\n\n<p>2.<strong>&nbsp; <\/strong>2015\u5e74\u570b\u7acb\u6210\u529f\u5927\u5b78\u512a\u79c0\u8ad6\u6587\u7af6\u8cfd \u512a\u52dd<\/p>\n\n\n\n<p>3.&nbsp; EMBO conference-Structure and function of the endoplasmic&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; reticulum Travel award, Girona, Spain, 23-27 October, 2016.<\/p>\n\n\n\n<p>4.&nbsp; 2017\u5e74 \u570b\u7acb\u6210\u529f\u5927\u5b78\u91ab\u7642\u5668\u6750\u5275\u65b0\u8a2d\u8a08(II) \u6210\u679c\u767c\u8868\u7af6\u8cfd \u7b2c\u4e00\u540d<\/p>\n\n\n\n<p>5.&nbsp; 2018\u5e74 \u570b\u7acb\u6210\u529f\u5927\u5b78\u7cbe\u5be6\u5275\u696d\u6210\u679c\u767c\u8868\u66a8\u5275\u696d\u7af6\u8cfd \u7b2c\u4e8c\u540d<\/p>\n\n\n\n<p>6.&nbsp; Best Poster Award. The 34<sup>th <\/sup>Joint of Annual Conference of Biomedical Science, Taipei, Taiwan. 23-24 Mar, 2019.<\/p>\n\n\n\n<p>7.&nbsp; 2019 \u53f0\u7063\u5927\u5b78\u751f\u7269\u6280\u8853\u7814\u7a76\u4e2d\u5fc3\u7b2c35\u5c46\u751f\u7269\u590f\u4ee4\u71df-\u69ae\u7372\u512a\u79c0\u5b78\u54e1<\/p>\n\n\n\n<p>8.&nbsp; 2021\u5e74\u5ea6\u79d1\u6280\u90e8\u7814\u7a76\u734e\u52f5 (\u734e\u52f5\u7279\u6b8a\u512a\u79c0\u4eba\u624d) -\u5f48\u6027\u85aa\u8cc7\u734e\u52f5 MOST Research Grants (Rewarding Outstanding Talent)<\/p>\n\n\n\n<p>9.&nbsp; Best Poster Award. The 37<sup>th <\/sup>Joint of Annual Conference of Biomedical Science, Taipei, Taiwan. 18-19 Mar, 2023.<\/p>\n\n\n\n<p>10.&nbsp; 2023 \u4e2d\u570b\u6bd2\u7406\u5b78\u6703\u7b2c\u4e5d\u5c46\u5168\u570b\u9752\u5e74\u79d1\u6280\u5927\u6703\u66a8\u7b2c\u4e8c\u5c46\u751f\u7269\u6280\u8853\u85e5\u7269\u6bd2\u7406\u8207\u5b89\u5168\u8a55\u50f9\u59d4\u54e1\u6703\u5b78\u8853\u6703\u8b70\u2014\u512a\u79c0\u8ad6\u6587\u734e<\/p>\n\n\n\n<p>11. 2024\u5e74\u5ea6\u570b\u79d1\u6703\u7814\u7a76\u734e\u52f5 (\u734e\u52f5\u7279\u6b8a\u512a\u79c0\u4eba\u624d) -\u5f48\u6027\u85aa\u8cc7\u734e\u52f5 NSTC Research Grants (Rewarding Outstanding Talent)<\/p>\n\n\n\n<p class=\"has-large-font-size\"><strong>\u4ee3 \u8868 \u8457 \u4f5c<\/strong><\/p>\n\n\n\n<ul>\n<li>C-C Chang, S-C Fan, Y-J Wang, J-W Ping, Y-H Su, J-C YANG, Y-X Chan, Y-X YANG,<strong><u> Y-H Lee<\/u><\/strong>, C-C Chang, C-H Lin, T-Y Juang *Hyperbranched Polymer Dots Enhance Hair Follicle Regeneration via Wnt\/\u03b2-Catenin Activation: A Drug-Free Nanozyme-Based Approach to Hair Growth Therapy. <strong><em>Biomedicine &amp; Pharmacotherapy<\/em><\/strong> 188():1-11 (2025) (S.C.I. Impact factor:&nbsp;<strong>7.5.<\/strong> Subject Category: 19\/352=5.4%&nbsp;in Pharmacology &amp; Pharmacy, JCR 2024)<\/li>\n\n\n\n<li><strong><u>Y-H Lee<\/u><\/strong>, C-M Zheng, Y-J Wang, Y-L Wang and H-W Chiu<strong>*<\/strong>. Effects of microplastics and nanoplastics on the kidney and cardiovascular system. <strong><em>Nature Reviews Nephrology<\/em><\/strong> (<em>In Press<\/em>) (S.C.I. Impact factor: <strong>39.8<\/strong>, 2\/133=1.5% in Urology &amp; Nephrology, JCR 2024) (<strong>First author<\/strong>) NSTC 113-2314-B-038-084 and NSTC 113-2314-B-039-044<\/li>\n\n\n\n<li>Y-L Wang<sup>#<\/sup>, Y-C Lin<sup>#<\/sup>, W-C Liu, <strong><u>Y-H Lee<sup>*<\/sup> <\/u><\/strong>and H-W Chiu<sup>*<\/sup>. Air pollution and its impacts on health: Focus on microplastics and nanoplastics. <strong><em>Ecotoxicology and Environmental Safety<\/em><\/strong> 299, 118402 (2025) (S.C.I. Impact factor: <strong>6.1<\/strong>. Subject Category: 10\/106=9.4% in Toxicology, JCR 2024) (<strong>Corresponding author<\/strong>) NSTC 113-2314-B-038-084 and NSTC 113-2314-B-039-044<\/li>\n\n\n\n<li>C-C Chang, H-M Lao, S-C Fan, Y-H Tu, J-C Siew, K-C Ma, <strong><u>Y-H Lee<\/u><\/strong>, H-M Chiang, C-C Chang, T Y Juang *. Bioactive hyperbranched polymer dot combined laser-induced optical breakdown for accelerating wound repair and regeneration in a nude mice mode. <strong><em>Materials Advances<\/em><\/strong> 6(10):3185-3202 (2025) (S.C.I. Impact factor: <strong>4.7.<\/strong> Subject Category: 207\/462=44.8% in MATERIALS SCIENCE, MULTIDISCIPLINARY, JCR 2024)<\/li>\n\n\n\n<li>H-W Chiu, C-W Chu, C-Ca Huan, Z-C Chia, Y-L Wang, <strong><u>Y-H Lee*<\/u><\/strong>. Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.<strong><em> Environmental Pollution<\/em><\/strong>&nbsp;369, 125850&nbsp;(2025).&nbsp;(S.C.I. Impact factor: <strong>7.3<\/strong>. Subject Category: 46\/374=12.3% in Environmental Sciences, JCR 2024) (<strong>Corresponding author) <\/strong>NSTC 113-2314-B-038-084 and NSTC 113-2314-B-039-044<\/li>\n\n\n\n<li>Y-H Cheng, H-I. Wu, Y-Y Chen, <strong><u>Y-H Lee<\/u><\/strong>, B-J Wang* and Y-J Wang*. Adverse outcome pathway-based approach to reveal the mechanisms of skin sensitization and long-term aging effects of chlorothalonil. <strong><em>Journal of Hazardous Materials<\/em><\/strong> 476, 135176 (2024). (S.C.I. Impact factor: <strong>11.3<\/strong>. Subject Category: 19\/374=5.1% in Environmental Sciences, JCR 2024)<\/li>\n\n\n\n<li>B-J Wang, Y-Y Chen, H-H Chang, R-J Chen, Y-J Wang* and<strong><u> Y-H Lee<\/u><\/strong><strong><u>*<\/u><\/strong>. Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury. <strong><em>Particle and Fibre Toxicology<\/em><\/strong>. 21, 9 (2024). (S.C.I. Impact factor: 8.2. Subject Category: 5\/106=4.7% in Toxicology, JCR 2024) &nbsp;<strong>(<\/strong><strong>Corresponding author<\/strong><strong>)<\/strong> NSTC 112-2314-B-039-044, CMU112-S-50.<a><\/a><\/li>\n\n\n\n<li>*. Oxidative stress and potential effects of metal nanoparticles: a review of biocompatibility and toxicity concerns.&nbsp;<strong><em>Environmental Pollution<\/em><\/strong>&nbsp;346, 123617&nbsp;(2024)&nbsp;(S.C.I. Impact factor: <strong>7.3<\/strong>. Subject Category: 46\/374=12.3% in Environmental Sciences, JCR 2024)<\/li>\n\n\n\n<li>Y-L Wang<sup>#<\/sup>, C C-Y Huang, C-M Zheng, W-C Liu, <strong><u>Y-H Lee<sup>#<\/sup><\/u><\/strong>&nbsp;and H-W Chiu*. Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.&nbsp;<strong><em>Ecotoxicology and Environmental Safety<\/em><\/strong>&nbsp;273, 116098 (2024) (S.C.I. Impact factor: <strong>6.1<\/strong>. Subject Category: 10\/106=9.4% in Toxicology, JCR 2024)<strong> (co-First author)<\/strong><\/li>\n\n\n\n<li>H-J Huang<sup>#<\/sup>, <strong><u>Y-H Lee<\/u><\/strong>, L-C Sung, Y-J Chen, Y-J Chiu, H-W Chiu<sup>#<\/sup> and C-M Zheng*. Drug repurposing screens to identify potential drugs for chronic kidney disease by targeting prostaglandin E2 receptor. <strong><em>Computational and Structural Biotechnology Journal<\/em><\/strong> 21, 3490\u20133502 (2023) (S.C.I. Impact factor: <strong>4.1<\/strong>. Subject Category: 104\/319=32.6% in Biochemistry &amp; Molecular Biology, JCR 2024) MOST 109-2314-B-038-078-MY3, MOST 110-2314-B-038-140, MOST 110-2314-B-039-018, MOST 110- 2314-B-038-075-MY3, MOST 111-2314-B-039-021, MOST 111-2314- B-038-154, MOST 111-2314-B-038-030, NSTC 112-2314-B-038-087 and NSTC 112-2314-B-039-044<\/li>\n\n\n\n<li>W-C Liu, H-W Chiu, C-L Chou, Y-J Chiu and <strong><u>Y-H Lee<\/u><\/strong><strong><u>*<\/u><\/strong>. Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2\/CENPE axis. <strong><em>Environmental Pollution<\/em><\/strong> 318, 120871 (2023). (S.C.I. Impact factor: <strong>7.3<\/strong>. Subject Category: 46\/374=12.3% in Environmental Sciences, JCR 2024) (<strong>Corresponding author)<\/strong> MOST 110-2314-B-039-018; MOST 111-2314-B-039-021<\/li>\n\n\n\n<li>C-M Zheng, K-C Lu, Y-J Chen, C-Y Li, <strong><u>Y-H Lee*<\/u><\/strong> and H-W Chiu*. Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy. <strong><em>Biomedicine &amp; Pharmacotherapy<\/em><\/strong> 154, 113565 (2022). (S.C.I. Impact factor:&nbsp;<strong>7.5.<\/strong> Subject Category: 19\/352=5.4%&nbsp;in Pharmacology &amp; Pharmacy, JCR 2024) (<strong>Corresponding author) <\/strong>MOST 110-2314-B-039-018; MOST 111-2314-B-039-021<\/li>\n\n\n\n<li>Z-Y Chen, Y-C Yang, B-J Wang, F-Y Cheng, Y-L Lee, <strong><u>Y-H Lee*<\/u><\/strong> and Y-J Wang<strong>*<\/strong>. Comparing different surface modifications of zinc oxide nanoparticles in the developmental toxicity of zebrafish embryos and larvae. <strong><em>Ecotoxicology and Environmental Safety <\/em><\/strong>243, 113967 (2022). (S.C.I. Impact factor: <strong>6.1<\/strong>. Subject Category: 10\/106=9.4% in Toxicology, JCR 2024)<strong> <\/strong>(<strong>Corresponding author)<\/strong> MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>H-J Huang, <strong><u>Y-H Lee<\/u><\/strong>, C-L Chou, C-M Zheng*and H-W Chiu*. Investigation of potential descriptors of chemical compounds on prevention of nephrotoxicity via QSAR approach. <strong><em>Computational and Structural Biotechnology Journal<\/em><\/strong> 20,1876-1884&nbsp;(2022). (S.C.I. Impact factor: <strong>4.1<\/strong>. Subject Category: 104\/319=32.6% in Biochemistry &amp; Molecular Biology, JCR 2024). MOST 108-2314-B-039-061-MY3, MOST 109-2314-B-038-078-MY3, MOST 110-2314-B-038-140 and MOST 110-2314-B-038-075-MY3<\/li>\n\n\n\n<li>W-C Liu<sup>#<\/sup>, H-C Chuang, C-L Chou, <strong>Y-H Lee<\/strong>, Y-J Chiu, Y-L Wang<sup>#<\/sup> and H-W Chiu*. Cigarette smoke exposure increases glucose-6-phosphate dehydrogenase, autophagy, fibrosis and senescence in kidney cells <em>in vitro<\/em> and <em>in vivo<\/em>. <strong><em>Oxidative Medicine and Cellular Longevity <\/em><\/strong>2022, 5696686<strong><em> <\/em><\/strong>(2022). MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>B-H Mao<sup>#<\/sup>, Y-K Luo, B-J Wang, C-W Chen, F-Y Cheng, <strong>Y-H Lee<\/strong><strong><sup>#<\/sup><\/strong>, S-J Yan*, Y-J Wang*. Use of an In silico Knowledge Discovery Approach to Determine Mechanistic Studies of Silver Nanoparticles-induced Toxicity from In vitro to In vivo.<strong><em> Particle and Fibre Toxicology<\/em><\/strong>. 19, 6 (2022). (S.C.I. Impact factor: <strong>8.2<\/strong>. Subject Category: 5\/106=4.7% in Toxicology, JCR 2024)<strong>(co-First author)<\/strong><\/li>\n\n\n\n<li>Y-Y Chen<strong><sup>#<\/sup><\/strong>, <strong>Y-H Lee<\/strong><strong><sup>#<\/sup><\/strong>, B-J Wang, R-J Chen, Y-J Wang. Skin Damage Induced by Zinc Oxide Nanoparticles Combined with UVB is Mediated by Activating Cell Pyroptosis via the NLRP3 Inflammasome-Autophagy-Exosomal Pathway. <strong><em>Particle and Fibre Toxicology<\/em><\/strong>. 19, 2 (2022). (S.C.I. Impact factor: <strong>8.2<\/strong>. Subject Category: 5\/106=4.7% in Toxicology, JCR 2024)<strong>(co-First author)<\/strong> MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>Y-L Wang<sup>#<\/sup>, <strong>Y-H Lee<\/strong>, Y-H Hsu, I-J Chiu, C C-Y Huang,&nbsp;C-C Huang, Z-C Chia,&nbsp;C-P Lee, Y-F Lin<sup>#<\/sup>&nbsp;and H-W Chiu*.&nbsp;The kidney-related effects of polystyrene microplastics on human kidney proximal tubular epithelial cells HK-2 and male C57BL\/6 mice.&nbsp;<strong><em>Environmental Health Perspectives<\/em><\/strong>&nbsp;129(5), 57003 (2021). (S.C.I. Impact factor: 9.8. Subject Category: 3\/106=2.8% in Toxicology, JCR 2024) MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>Y-L Wang, C-M Zheng, <strong>Y-H Lee<\/strong>, Y-Y Cheng, Y-F Lin and H-W Chiu*. Micro- and nanosized substances cause different autophagy-related responses.&nbsp;<strong><em>International Journal of Molecular Sciences<\/em><\/strong><strong><em>&nbsp;<\/em><\/strong>22, 4787 (2021). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024) MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>H-J Huang,&nbsp;<strong>Y-H Lee<\/strong>,&nbsp;Y-H Hsu, C-T Liao, Y-F Lin* and&nbsp;H-W Chiu*. Current strategies in assessment of nanotoxicity: Alternatives to&nbsp;<em>in vivo<\/em>&nbsp;animal testing.&nbsp;<strong><em>International Journal of Molecular Sciences<\/em><\/strong><strong><em>&nbsp;<\/em><\/strong>22, 4216 (2021). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024) MOST108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>Y-H Hsu<sup>#<\/sup>, C-M Zheng, C-L Chou, Y-J Chen, <strong>Y-H Lee<sup>#<\/sup><\/strong>, Y-F Lin*, H-W Chiu*. Therapeutic effect of endothelin-converting enzyme inhibitor on chronic kidney disease through the inhibition of endoplasmic reticulum stress and the NLRP3 inflammasome. <strong><em>Biomedicines<\/em><\/strong> 9, 398 (2021). (S.C.I. Impact factor: <strong>3.9.<\/strong> Subject Category: 88\/352=25.0% in Pharmacology &amp; Pharmacy, JCR 2024) <strong>(co-First author)<\/strong> MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>R\u2011J Chen<sup>#<\/sup>, C-C Huang, R Pranata, <strong>Y\u2011H Lee<\/strong><strong><sup>#<\/sup><\/strong>, Y-Y Chen, Y-H Wu*, Y\u2011J Wang*. Modulation of innate immune toxicity by silver nanoparticle exposure and the preventive effects of pterostilbene.<strong><em>International Journal of Molecular Sciences<\/em><\/strong> 22, 2536 (2021). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024) <strong>(co-First author)<\/strong> MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>R\u2011J Chen<sup>#<\/sup>, <strong>Y\u2011H Lee<\/strong><strong><sup>#<\/sup><\/strong>, T\u2011H Chen, Y\u2011Y Chen, Y\u2011L Yeh, C\u2011P Chang, C\u2011C Huang, H-R Guo*, Y\u2011J Wang*. Carbon monoxide\u2011triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes. <strong><em>Archives of Toxicology<\/em><\/strong> 95(4):1141-1159 (2021). (<a>S.C.I. Impact factor: <strong>4.8<\/strong>. Subject Category: 14\/106=13.2% in <\/a>Toxicology, JCR 2023).<strong> (co-First author)<\/strong> MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>C-M Zheng<sup>#<\/sup>, <strong><u>Y-H Lee<\/u><\/strong>, I-J Chiu, Y-J Chiu, L-C Sung, Y-H Hsu and H-W Chiu*. Nicotine Causes Nephrotoxicity through the Induction of NLRP6 Inflammasome and Alpha7 Nicotinic Acetylcholine Receptor. <strong><em>Toxics<\/em><\/strong> 8(4), 92 (2020). (S.C.I. Impact factor: <strong>4.1<\/strong>. Subject Category: 23\/106=21.7% in Toxicology, JCR 2024). MOST 108-2314-B-039-061-MY3<\/li>\n\n\n\n<li>Y-H Hsu<sup>#<\/sup>, I-J Chiu, Y-F Lin, Y-J Chen, <strong><u>Y-H Lee<\/u><\/strong><sup>#<\/sup> and H-W Chiu*. Lactoferrin contributes a renoprotective effect in acute kidney injury and early renal fibrosis. <strong><em>Pharmaceutics<\/em><\/strong> 12(5), 434 (2020). (S.C.I. Impact factor: <strong>5.5<\/strong>. Subject Category: 34\/352=9.7% in Pharmacology &amp; Pharmacy, JCR 2024). <strong>(co-First author) <\/strong>MOST 108-2314-B-039-061-MY3.&nbsp;&nbsp;<\/li>\n\n\n\n<li>Z-Y Chen, N-J Li, F-Y Cheng, J-F Hsueh, C-C Huang, F-I Lu, T-F Fu,<strong> <\/strong>S-J Yan<strong>,<\/strong> <strong><u>Y-H Lee*<\/u><\/strong> and Y-J Wang*. The effect of chorion on size-dependent developmental toxicity and underlying mechanisms of amine-modified silver nanoparticles in zebrafish embryo.<strong><em>International Journal of Molecular Sciences<\/em><\/strong> 21, 2864 (2020). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<strong> (Corresponding author)<\/strong> MOST 108-2314-B-039-061-MY3.<\/li>\n\n\n\n<li>R-J Chen, Y-Y Chen, M-Y Liao, <strong><u>Y-H Lee<\/u><\/strong>, Z-Y Chen, S-J Yan, Y-L Yeh, Y-L Lee, L-X Yang, Y-H Wu *and Ying-Jan Wang *. The current understanding of autophagy in nanomaterials toxicity and its implementation in safety assessment related alternative testing strategy. <strong><em>International Journal of Molecular Sciences<\/em><\/strong><strong><em> <\/em><\/strong>21(7), 2387 (2020) (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<\/li>\n\n\n\n<li>Y-L Wang, <strong><u>Y-H Lee<\/u><\/strong>, I-J Chiu, Y-F Lin* and H-W Chiu*. Potent impact of plastic nanomaterials and micromaterials on the food chain and human health. <strong><em>International Journal of Molecular Sciences<\/em><\/strong> 21(5), 1727 (2020). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<\/li>\n\n\n\n<li>F-Y Cheng#, <strong><u>Y-H Lee<\/u><\/strong>, Y-H Hsu, I-J Chiu, Y-J Chiu, Y-F Lin# and H-W Chiu*. Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1. <strong><em>Aging (Albany NY) <\/em><\/strong>12;11(21):9875-9892 (2019). (S.C.I. Impact factor: <strong>3.9<\/strong>. Subject Category: 24\/74=32.4% in Geriatrics &amp; Gerontology, JCR 2024)<\/li>\n\n\n\n<li>Y-H Hsu<sup>#<\/sup>, H-C Chuang, <strong><u>Y-H Lee<\/u><\/strong>, Y-F Lin, Y-J Chiu, Y-L Wang<sup>#<\/sup>, M-S Wu*and H-W Chiu*. Induction of fibrosis and autophagy in kidney cells by vinyl chloride. <strong><em>Cells<\/em><\/strong> 8, 601 (2019). (S.C.I. Impact factor:<strong>&nbsp;5.2<\/strong>. Subject Category: 59\/204=28.9% in Cell Biology, JCR 2024)<\/li>\n\n\n\n<li><strong><u>Y-H Lee<\/u><\/strong><sup>#<\/sup>, Y-Y Chen<sup>#<\/sup>, Y-L Yeh, Y-J Wang* and R-J Chen*. Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity. <strong><em>International Journal of Molecular Sciences<\/em><\/strong> 20: 2716 (2019). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<strong> (co-First author)<\/strong><\/li>\n\n\n\n<li>Y-H Hsu<sup>#<\/sup>, H-C Chuang, <strong><u>Y-H Lee<\/u><\/strong>, Y-F Lin, Y-J Chen, T-C Hsiao, M-Y Wu<sup>#<\/sup> and H-W Chiu*. Traffic-related particulate matter exposure induces nephrotoxicity&nbsp;<em>in vitro<\/em>&nbsp;and&nbsp;<em>in vivo<\/em>. <strong><em>Free Radical Biology &amp; Medicine<\/em><\/strong> 135: 235-244 (2019)&nbsp;(S.C.I. Impact factor:<strong>&nbsp;8.2<\/strong>. Subject Category: 14\/191=7.3% in Endocrinology &amp; Metabolism, JCR 2024)<\/li>\n\n\n\n<li>B-J Wang, H-W Chiu, Y-Lin Lee, C-Yi Li, Y-J Wang<strong>*<\/strong> and <strong><u>Y-H Lee<\/u>*<\/strong>. Pterostilbene attenuates hexavalent chromium-induced allergic contact dermatitis by preventing cell apoptosis and inhibiting IL-1\u03b2-related NLRP3 inflammasome activation. <strong><em>Journal of Clinical Medicine<\/em><\/strong> 7(12), 489 (2018) (S.C.I. Impact factor:<strong>&nbsp;2.9<\/strong>. Subject Category: 65\/332=19.6% in Medicine, General &amp; Internal, JCR 2024).<strong> <\/strong>MOST 107-2314-B-006-007. <strong>(Corresponding author)<\/strong><\/li>\n\n\n\n<li>R-J Chen, H-C Kuo, L-H Cheng, <strong><u>Y-H Lee<\/u><\/strong>, W-T Chang, B-J Wang, Y-J Wang and H-C Cheng. Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer.<strong><em>International Journal of Molecular Sciences<\/em><\/strong> 19(1), 287 (2018). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<\/li>\n\n\n\n<li>Y-F Lin, <strong><u>Y-H Lee<\/u><\/strong>, Y-H Hsu, Y-J Chen, Y-F Lin, F-Y Cheng and H-W Chiu. Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease. <strong><em>Nanomedicine<\/em><\/strong> 12(22):2741-2756 (2017) (S.C.I. Impact factor: <strong>3.9<\/strong>. Subject Category: 54\/177=30.5% in Biotechnology &amp; Applied Microbiology, JCR 2024)<\/li>\n\n\n\n<li><strong><u>Y-H Lee<\/u><\/strong>, C-Y Fang,&nbsp;H-W Chiu, F-Y Cheng, J-C Tsai, C-W Chen and Y-J Wang. Endoplasmic reticulum stress-triggered autophagy and lysosomal dysfunction contribute to the cytotoxicity of amine-modified silver nanoparticles in NIH 3T3 cells.&nbsp;<strong><em>Journal of Biomedical Nanotechnology&nbsp;<\/em><\/strong>13: 778\u2013794 (2017) <strong>(First author)<\/strong><\/li>\n\n\n\n<li>R-J Chen, <strong><u>Y-H Lee<\/u><sup>#<\/sup><\/strong>, Y-L Yeh, W-S Wu, C-T Ho, C-Y Li, Y-J Wang and B-J Wang. Autophagy-inducing Effect of Pterostilbene: a Prospective Therapeutic\/Preventive Option for Skin Diseases. <strong><em>J Food Drug Anal.<\/em><\/strong> 25:125-133 (2017) (<a>S.C.I. Impact factor:&nbsp;<strong>2.6.<\/strong> Subject Category: 85\/173=49.1% in Food Science and Technology, JCR&nbsp;202<\/a>3)<strong> (co-First author)<\/strong><\/li>\n\n\n\n<li>\u694a\u7fca\u7fa3\u3001<strong><u>\u674e\u5ba5\u8431<\/u><\/strong>\u3001\u9673\u7d89\u654f\u3001\u6bdb\u5f6c\u65ed\u3001\u9673\u6625\u842c\u3001\u738b\u61c9\u7136\u3002\u5948\u7c73\u5fae\u7c92\u5371\u5bb3\u5206\u7d1a\u7ba1\u7406\u9069\u7528\u6027\u4e4b\u63a2\u8a0e-\u4ee5\u5948\u7c73\u6c27\u5316\u92c5\u70ba\u4f8b\u3002\u52de\u52d5\u53ca\u8077\u696d\u5b89\u5168\u885b\u751f\u7814\u7a76\u5b63\u520a\uff0c\u6c11\u570b106\u5e749\u6708\u7b2c25\u5377\u7b2c3\u671f\u7b2c143-227\u9801\u3002<\/li>\n\n\n\n<li>R-J Chen, <strong><u>Y-H Lee<\/u><sup>#<\/sup><\/strong>, Y-L Yeh, Y-J Wang and B-J Wang. The Roles of Autophagy and the Inflammasome during Environmental Stress-Triggered Skin Inflammation. <strong><em>International Journal of Molecular Sciences<\/em><\/strong> 17(12):2063 (2016). (S.C.I. Impact factor: <strong>4.9<\/strong>. Subject Category: 72\/319=22.6% in Biochemistry &amp; Molecular Biology, JCR 2024)<strong> <\/strong><strong>(co-First author)<\/strong><\/li>\n\n\n\n<li>Y-F Lin,&nbsp;I-J Chiu,&nbsp;F-Y Cheng,&nbsp;<strong><u>Y-H Lee<\/u><\/strong>, Y-J Wang, Y-H Hsu and&nbsp;H-W Chiu.&nbsp;The role of hypoxia-inducible factor-1\u03b1&nbsp;in zinc oxide nanoparticle-induced nephrotoxicity&nbsp;<em>in vitro&nbsp;<\/em>and <em>in vivo.&nbsp;<strong>Particle and Fibre Toxicology<\/strong><\/em>. 13:52 (2016). (S.C.I. Impact factor: <strong>8.2<\/strong>. Subject Category: 5\/106=4.7% in Toxicology, JCR 2024)<\/li>\n\n\n\n<li><strong><u>\u674e\u5ba5\u8431<\/u><\/strong>\u3001\u65b9\u6625\u8a60\u3001\u9673\u6625\u842c\u3001\u738b\u61c9\u7136\u3002\u5948\u7c73\u5fae\u7c92\u5371\u5bb3\u6e2c\u8a66\u6280\u8853\u8207\u751f\u7269\u6bd2\u6027\u6307\u6a19\u4e4b\u63a2\u8a0e\u3002\u52de\u52d5\u53ca\u8077\u696d\u5b89\u5168\u885b\u751f\u7814\u7a76\u5b63\u520a\uff0c\u6c11\u570b105\u5e749\u6708\u7b2c24\u5377\u7b2c3\u671f\u7b2c330-342\u9801\u3002<\/li>\n\n\n\n<li>H-M Chen,&nbsp;<strong><u>Y-H Lee<\/u><\/strong><strong><sup>#<\/sup><\/strong>, Y-J Wang. ROS-Triggered Signaling Pathways Involved in the Cytotoxicity and Tumor Promotion Effects of Pentachlorophenol and Tetrachlorohydroquinone. <strong><em>Chemical Research in Toxicology<\/em><\/strong> 28(3):339-50 (2015). (S.C.I. Impact factor:<strong>3.7<\/strong> Subject Category: 29\/72=40.2% in Chemistry, Medicinal, JCR 2023) <strong>(co-First author)<\/strong><\/li>\n\n\n\n<li>H-W Chiu,<sup> <\/sup>T Xia, <strong><u>Y-H Lee<\/u><\/strong>,C-W Chen,J-C Tsai, and Y-J Wang<strong> *<\/strong>. Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress. <strong><em>Nanoscale. <\/em><\/strong>7(2):736-462 (2015)<em>&nbsp;<\/em>(S.C.I. Impact factor:&nbsp;<strong>5.1<\/strong>. Subject Category: 45\/187=24.1% in&nbsp;Physics, Applied, JCR 2024)<\/li>\n\n\n\n<li><strong><u>Y-H Lee<\/u><\/strong>,&nbsp;F-Y Cheng,&nbsp;H-W Chiu, J-C Tsai,&nbsp;C-Y Fang, C-W Chen and Y-J Wang. Cytotoxicity, oxidative stress, apoptosis and the autophagic effects of silver nanoparticles in&nbsp;mouse embryonic fibroblasts. <strong><em>Biomaterials <\/em><\/strong>35: 4706-4715&nbsp;(2014)&nbsp;(S.C.I. Impact factor:<strong> 12.9<\/strong>. Subject Category: 5\/124=4.0% in Engineering, Biomedical, JCR 2024) NSC 102-2314-B-006-034 <strong>(First author)<\/strong><\/li>\n\n\n\n<li>J-W Guo, <strong><u>Y-H Lee<\/u><\/strong>, H-W Huang, M-C Tzou, Y-J Wang, J-C Tsai. Development of Taiwan\u2019s strategies for regulating nanotechnology-based pharmaceuticals harmonized with international considerations.<strong><em> International Journal of Nanomedicine<\/em><\/strong>&nbsp;9:4773-4783 (2014) (S.C.I. Impact factor: <strong>6.6<\/strong>. Subject Category: 20\/354 =5.6% in Pharmacology &amp; Pharmacy, JCR 2023)<\/li>\n\n\n\n<li><strong><u>Y-H Lee<\/u><\/strong>, S-B Su, C-C Huang, H-M Sheu, J-C Tsai, C-H Lin, Y-J Wang, B-J Wang. N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression. <strong><em>PLoS ONE<\/em><\/strong>. 9: e108317 (2014) (S.C.I. Impact factor: <strong>2.6<\/strong>. Subject Category: 44\/135 =32.6% in Multidisciplinary Sciences, JCR 2024) NSC-102-2314-B-006-034 <strong>(First author)<\/strong><\/li>\n\n\n\n<li>H-M Chen,&nbsp;<strong><u>Y-H Lee<\/u><\/strong>, R-J Chen,&nbsp;H-W Chiu, B-J Wangand Y-J Wang.&nbsp;The immunotoxic effects of&nbsp;dual exposure to&nbsp;PCP and TCDD.&nbsp;<strong><em>Chemico-Biological Interactions<\/em><\/strong>&nbsp;206:166-174&nbsp;(2013) (S.C.I. Impact factor: <strong>5.4<\/strong>. Subject Category: 38\/352=10.8% in Pharmacology &amp; Pharmacy, JCR 2024)&nbsp;NSC 101-2314-B-006-050 <strong>(co-First author)<\/strong><\/li>\n\n\n\n<li>N-P Foo, S-H Lin<strong>,<\/strong> <strong><u>Y-H Lee<\/u><\/strong>, M-J Wu, Y-J Wang*. \u03b1-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-\u03b2. <strong><em>Toxicology<\/em><\/strong> 282: 39-46 (2011) (S.C.I. Impact factor: <strong>4.8<\/strong>. Subject Category:&nbsp;14\/106=13.2% in Toxicology, JCR 2023) NSC 98-2314-B-006-034-MY2<\/li>\n\n\n\n<li>B-J Wang, H-M Sheu, Y-Lg Guo, <strong><u>Y-H Lee<\/u><\/strong>, C-S Lai, M-H Pan, Y- J Wang*. Hexavalent chromium-induced ROS formation, Akt, NF-\u03baB, and MAPK activation, and TNF-\u03b1 and IL-1\u03b1 production in keratinocytes. <strong><em>Toxicology Letters<\/em><\/strong> 198: 216-224 (2010) (S.C.I. Impact factor:<strong> 2.9<\/strong>. Subject Category:&nbsp;49\/106=46.2% in Toxicology, JCR 2023) NSC 98-2314-B-006-034-MY2<\/li>\n\n\n\n<li>B-J Wang, Y-L Guo, H-Y Chang, H-M Sheu, M-H Pan, <strong><u>Y-H Lee<\/u><\/strong> and Y-J Wang*. N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species. <strong><em>Experimental Dermatology<\/em><\/strong> 19: e191-e200 (2010) (S.C.I. Impact factor: <strong>3.5<\/strong>. Subject Category: 20\/94 =21.2% in Dermatology, JCR 2023) NSC-95-2314-B-006-095-MY3<\/li>\n<\/ul>\n\n\n\n<p>B. \u7814\u8a0e\u6703\u8ad6\u6587<\/p>\n\n\n\n<ul>\n<li>, <strong><u>Yu-Hsuan Lee<\/u><\/strong>. CSF2-Driven Inflammasome Activation and Senescence Mediate Particulate Matter\u2013Induced Renal Injury. The 15th National Conference in Toxicology (NCT15), Bangkok, Thailand, Sep. 3-4, 2025.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Particulate matter promotes the development of atopic dermatitis by inhibiting TREX1 and activating the inflammasome pathway. <a>The 49th FEBS Congress. Istanbul, Turkey, July 5-9, 2025<\/a>.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Particulate matter exacerbates kidney damage by increasing the CSF2, inflammasomes, and senescence. The Asian Pacific Congress of Nephrology 2024 in conjunction with the 44<sup>th <\/sup>Annual Meeting of the Korean Society of Nephrology. Coex, Seoul, Korea. June 13-16, 2024.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee.<\/u><\/strong> Particulate Matter (PM) causes skin barrier dysfunction : The exacerbation of on Atopic Dermatitis. The 38<sup>th<\/sup> Joint of Annual Conference of Biomedical Science, Taipei, Taiwan. 23-24 Mar, 2024.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>2023 \u5e7410\u670829-31 \u65e5\u3002<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Naringin regulated macrophage differentiation to promote wound healing by affecting the expression of CMPK2. 10<sup>th<\/sup> International Congress of Asian Society of Toxicology (ASIATOX-X). NTUH International Convention Center, Taipei, Taiwan. July 17-20, 2023.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Yu-Hsuan Huang, Hui-Wen Chiu and <strong><u>Yu-Hsuan Lee<\/u><\/strong>. The role of autophagy regulated-NLRP3 inflammasome inactivation in the therapy of alcoholic liver disease. 9<sup>th<\/sup> International Congress of Asian Society of Toxicology (ASIATOX-IX). Hangzhou, Zhejiang Province, China (Online). October 20-23, 2021.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Yuh-Feng Lin, <strong><u>Yu-Hsuan Lee<\/u><\/strong> and Hui-Wen Chiu. Crosstalk between endoplasmic reticulum stress and autophagy in kidney diseases. International Society for Extracellular Vesicles (ISEV) Annual Meeting 2019. Kyoto, Japan, 24-28 April 2019.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li>Yi-Kai Lou, Ying-Jan Wang, <strong><u>Yu-Hsuan Lee<\/u><\/strong>. Hazard estimation of silver nanoparticles in different cellular models using methods of knowledge discovery from data. The 43<sup>rd<\/sup> FEBS 2018 Congress. Prague, Czech Republic, 7-12 July, 2018.<strong><\/strong><\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Yung-Lin Li, Bour-Jr Wang and Ying-Jan Wang. Interference in apoptosis and endoplasmic reticulum stress by pterostilbene assists autophagy in regulating an interleukin-1\u03b2 in the hexavalent chromium-induced allergic contact dermatitis. EMBO Conference- Structure and function of the endoplasmic reticulum. Girona, Spain, 23-27 October, 2016.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Chun-Wan Chenand Ying-Jan Wang. Induction of Autophagy and Cytotoxicity by Different Sized Silver Nanoparticles in NIH 3T3 Cells. The 9th IEEE international Conference on Nano\/Molecular Medicine and Engineering. Waikiki Beach, Hhawaii, USA, 15-18 November, 2015.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Bour-Jr Wang, and Ying- Jan Wang. N-acetylcysteine inhibits hexavalent chromium-induced cell death and TNF-\u03b1 and IL-1\u03b1 expression, thereby preventing the development of chromium hypersensitivity. Cell Death Mechanisms at the Interface of Health and Disease (Gordon Research Conferences). West Dover, VT, USA, 8-13 June, 2014.<strong><\/strong><\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Chun-Wan Chen, Jui-Chen Tsai, Ying-Jan Wanga. Study on the contributing factors of cytotoxicity and adverse index of silver nanoparticle by using mammalian cell lines. 4th International Nanomedicine Conference. Sydney, Australia, 1-3 July, 2013.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Yung-Lin Li and Ying-Jan Wang. The mechanism of antioxidants suppressed the hexavalent chromium-induced allergic contact dermatitis. 3rd EMBO Conference Series on Cellular Signaling &amp;Molecular Medicine. Dubrovnik, Cavtat, 25 &#8211; 29 May, 2012.<\/li>\n<\/ul>\n\n\n\n<ul>\n<li><strong><u>Yu-Hsuan Lee<\/u><\/strong>, Sheng-Yow Ho, Wen-Hung Fang and Ying-Jan Wang. The possible chemopreventive effects of Monascus on prostate related disease and the enhanced therapeutic potency for prostate cancer combined with irradiation. Warszawa, Poland, 28 August \u2013 1 September, 2011.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u674e\u5ba5\u8431 \u526f\u6559\u6388 \u5b78\u6b77 \u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u535a\u58eb \u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u78a9\u58eb \u4e2d\u5c71\u91ab\u5b78\u5927\u5b78\/\u8077 &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/ieohs.nycu.edu.tw\/?p=4445\">  \u95b1\u8b80\u5168\u6587 &raquo;<\/a><\/p>\n","protected":false},"author":10,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":""},"categories":[64],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>- NYCU_IEOHS<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ieohs.nycu.edu.tw\/?p=4445\" \/>\n<meta property=\"og:locale\" content=\"zh_TW\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"- NYCU_IEOHS\" \/>\n<meta property=\"og:description\" content=\"\u674e\u5ba5\u8431 \u526f\u6559\u6388 \u5b78\u6b77 \u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u535a\u58eb \u570b\u7acb\u6210\u529f\u5927\u5b78\/\u74b0\u5883\u91ab\u5b78\u7814\u7a76\u6240\/\u78a9\u58eb \u4e2d\u5c71\u91ab\u5b78\u5927\u5b78\/\u8077 &hellip; 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